(E)-5-羟基-7h-吡啶并[2,3-b]氮杂革-8(9h)-酮合成路线 (共 2 条)
反应条件
water in dimethyl sulfoxide
T=150°C;
参考文献
Kunick, Conrad; Lauenroth, Kathrin; Leost, Maryse; Meijer, Laurent; Lemcke, Thomas
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 2 p. 413 - 416
反应条件
1: 39 percent / NaH / toluene / 90 °C
2: 81 percent / H2O / dimethylsulfoxide / 150 °C
View Scheme
参考文献
Kunick, Conrad; Lauenroth, Kathrin; Leost, Maryse; Meijer, Laurent; Lemcke, Thomas
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 2 p. 413 - 416