2-苄氧基-5-甲酰基乙酸苯酯合成路线 （共 8 条）
参考文献
Li, Pixu; Evans, Cory D.; Wu, Yongzhong; Cao, Bin; Hamel, Ernest; Joullie, Madeleine M.
Journal of the American Chemical Society, 2008 , vol. 130, # 7 p. 2351 - 2364
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=0°C; 0.5 h;
参考文献
Sawayama, Andrew M.; Tanaka, Hiroko; Wandless, Thomas J.
Journal of Organic Chemistry, 2004 , vol. 69, # 25 p. 8810 - 8820
反应条件
triphenylphosphine; diethylazodicarboxylate in tetrahydrofuran; toluene
T=0 - 20°C; Inert atmosphere;
参考文献
Fumeaux, Rene; Menozzi-Smarrito, Candice; Stalmach, Angelique; Munari, Caroline; Kraehenbuehl, Karin; Steiling, Heike; Crozier, Alan; Williamson, Gary; Barron, Denis
Organic and Biomolecular Chemistry, 2010 , vol. 8, # 22 p. 5199 - 5211
参考文献
Li, Pixu; Evans, Cory D.; Joullie, Madeleine M.
Organic Letters, 2005 , vol. 7, # 23 p. 5325 - 5327
反应条件
triethylamine in tetrahydrofuran
T=20°C; 1 h;
参考文献
SUMITOMO CHEMICAL CO LTD
Patent: JP2005/314352 A, 2005 ;
Location in patent: Page/Page column 59 ;
参考文献
Li, Pixu; Evans, Cory D.; Joullie, Madeleine M.
Organic Letters, 2005 , vol. 7, # 23 p. 5325 - 5327
反应条件
1.1: 99 percent / AgSbF6; [(S)-2,2'-bis(2-OH-3,5-di-tBu-C6H2-CH=N)-1,1'-biNaphth]Al
2.1: 95 percent / K2CO3; MeOH / tetrahydrofuran
3.1: 70 percent / Pd2(dba)3*CHCl3; (S,S)-1,2-bis(2-Ph2P-C6H4-CONH)cyclohexane
4.1: 72 percent / K2OsO4*H2O; (DHQD)2PYR
5.1: TEMPO; NaOCl
6.1: NaClO2
7.1: 95 percent / BOP
8.1: LiN3
9.1: PMe3
10.1: BOP
11.2: NaBH4
12.1: (COOOH)2
13.1: LiOH / 0 °C
14.1: TFA / CH2Cl2 / 0 °C
15.1: 56 percent / PyAOP; Hunig's base
16.1: H2 / Pd/C
17.1: LiOH / 20 °C
View Scheme
参考文献
Tanaka, Hiroko; Sawayama, Andrew M.; Wandless, Thomas J.
Journal of the American Chemical Society, 2003 , vol. 125, # 23 p. 6864 - 6865
反应条件
hydrogen; calcium carbonate; palladium on activated charcoal in ethanol
参考文献
Su,T.-L. et al.
Chemische Berichte, 1977 , vol. 110, p. 3867 - 3873
