N-苄基-1-氮杂双环[2.2.2]-3-辛胺合成路线 （共 2 条）
反应条件
1: (RS)-3-amino-1-azabicyclo[2.2.2]octane dihydrochloride With sodium carbonate in ethanol
1 h;
2: benzaldehyde in ethanol
T=20°C; 2 h;
3: With sodium tetrahydroborate in ethanol
T=20°C;
参考文献
JANSSEN PHARMACEUTICA, N.V.
Patent: WO2004/35574 A2, 2004 ;
Location in patent: Page 30 ;
WO 2004/035574 A2
反应条件
Potassium borohydride; benzaldehyde in methanol; water; toluene
参考文献
Delalande S.A.
Patent: US4657911 A1, 1987 ;
