(R)-(+)-2-(4-羟基苯氧基)丙酸乙酯合成路线 （共 17 条）
反应条件
hydrogen; palladium on activated charcoal in ethanol T=20°C; 5 h;
参考文献
Kato, Dai-Ichiro; Mitsuda, Satoshi; Ohta, Hiromichi
Journal of Organic Chemistry, 2003 , vol. 68, # 19 p. 7234 - 7242
反应条件
potassium carbonate; acetic acid in ethanol
参考文献
ICI Australia Limited
Patent: US4837355 A1, 1989 ;
反应条件
potassium hydroxide in dimethyl sulfoxide T=0 - 30°C; Inert atmosphere;
参考文献
Zheng, Jian-Yong; Wu, Jia-Yu; Zhang, Yin-Jun; Wang, Zhao
Journal of Molecular Catalysis B: Enzymatic, 2013 , vol. 97, p. 62 - 66
反应条件
anhydrous sodium hydrogen carbonate; sodium hydrogen sulphite; 3-chloro-benzenecarboperoxoic acid in dichloromethane; water
反应条件
Yield given. Multistep reaction;
参考文献
Australian Journal of Chemistry, , vol. 48, # 8 p. 1503 - 1510
反应条件
sodium ethanolate in ethanol T=0 - 35°C; 6 h;
参考文献
Liu, Hui; Wang, Hong-Qing; Ding, Ming-Wu; Liu, Zhao-Jie; Xiao, Wen-Jing
Journal of Fluorine Chemistry, 2006 , vol. 127, # 12 p. 1584 - 1590
反应条件
sulfuric acid in ethanol
反应条件
1: 91 percent / sodium hydride / tetrahydrofuran / 14 h / 20 °C 2: 100 percent / hydrogen / Pd/C / ethanol / 5 h / 20 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 68, # 19 p. 7234 - 7242
反应条件
1: 91 percent / sodium hydride / tetrahydrofuran / 14 h / 20 °C 2: 100 percent / hydrogen / Pd/C / ethanol / 5 h / 20 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 68, # 19 p. 7234 - 7242
反应条件
1: K2CO3 / dimethylformamide; xylene 2: AcOH / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 13 p. 1709 - 1713
