2-(4-羟基苯氧基)-2-甲基丁酸甲酯合成路线 （共 6 条）
反应条件
hydrogen; palladium on activated charcoal
参考文献
Desai, Ranjit C.; Metzger, Edward; Santini, Conrad; Meinke, Peter T.; Heck, James V.; Berger, Joel P.; MacNaul, Karen L.; Cai, Tian-Quan; Wright, Samuel D.; Agrawal, Arun; Moller, David E.; Sahoo, Soumya P.
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 6 p. 1673 - 1678
反应条件
1: LDA / tetrahydrofuran / -78 °C
2: H2 / Pd/C
View Scheme
参考文献
Desai, Ranjit C.; Metzger, Edward; Santini, Conrad; Meinke, Peter T.; Heck, James V.; Berger, Joel P.; MacNaul, Karen L.; Cai, Tian-Quan; Wright, Samuel D.; Agrawal, Arun; Moller, David E.; Sahoo, Soumya P.
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 6 p. 1673 - 1678
反应条件
1: Cs2CO3 / acetonitrile
2: LDA / tetrahydrofuran / -78 °C
3: H2 / Pd/C
View Scheme
参考文献
Desai, Ranjit C.; Metzger, Edward; Santini, Conrad; Meinke, Peter T.; Heck, James V.; Berger, Joel P.; MacNaul, Karen L.; Cai, Tian-Quan; Wright, Samuel D.; Agrawal, Arun; Moller, David E.; Sahoo, Soumya P.
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 6 p. 1673 - 1678
反应条件
1: Cs2CO3 / acetonitrile
2: LDA / tetrahydrofuran / -78 °C
3: H2 / Pd/C
View Scheme
参考文献
Desai, Ranjit C.; Metzger, Edward; Santini, Conrad; Meinke, Peter T.; Heck, James V.; Berger, Joel P.; MacNaul, Karen L.; Cai, Tian-Quan; Wright, Samuel D.; Agrawal, Arun; Moller, David E.; Sahoo, Soumya P.
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 6 p. 1673 - 1678
反应条件
chiral resolution using Chiracel OJ column;
参考文献
MERCK and CO., INC.
Patent: WO2004/10992 A1, 2004 ;
Location in patent: Page/Page column 34 ;
WO 2004/010992 A1
反应条件
chiral resolution using Chiracel OJ column;
参考文献
MERCK and CO., INC.
Patent: WO2004/10992 A1, 2004 ;
Location in patent: Page/Page column 34 ;
WO 2004/010992 A1
