1: With potassium hydroxide 2: With hydrogenchloride

potassium tert-butylate in tert-butyl alcohol T=35°C; 2 h;

1: With sodium hypochlorite 2: With sodium hydrogensulfite

1.1: n-BuLi / tetrahydrofuran 1.2: iodine / tetrahydrofuran 2.1: NH3; TiCl4 / tetrahydrofuran 3.1: sodium hypochlorite 3.2: 78 percent / sodium hydrogensulfite View Scheme

1.1: 1,2-dichloro-ethane; benzotriazol-1-ol / dichloromethane / 0.5 h / 0 °C 1.2: 20 °C 2.1: sodium hydride / N,N-dimethyl-formamide / 0 - 20 °C 3.1: potassium tert-butylate / tert-butyl alcohol / 0 - 20 °C / |Inert atmosphere View Scheme

1.1: 1,2-dichloro-ethane; benzotriazol-1-ol / dichloromethane / 0.5 h / 0 °C 1.2: 20 °C 2.1: sodium hydride / N,N-dimethyl-formamide / 0 - 20 °C 3.1: potassium tert-butylate / tert-butyl alcohol / 0 - 20 °C / |Inert atmosphere View Scheme

1.1: chloroform / 2 h / 20 °C 2.1: hydrogen bromide / methanol / 0 - 20 °C 3.1: 1,2-dichloro-ethane; benzotriazol-1-ol / dichloromethane / 0.5 h / 0 °C 3.2: 20 °C 4.1: sodium hydride / N,N-dimethyl-formamide / 0 - 20 °C 5.1: potassium tert-butylate / tert-butyl alcohol / 0 - 20 °C / |Inert atmosphere View Scheme