2-氰基-2-(5-溴嘧啶-2)乙酸乙酯合成路线 （共 3 条）
反应条件
1: With sodium chloride in water; dimethyl sulfoxide T=120°C; 3 h; 2: With sodium hydroxide in water
参考文献
BAYER CROPSCIENCE SA
Patent: WO2006/117358 A1, 2006 ;
Location in patent: Page/Page column 37 ;
反应条件
1: cyanoacetic acid ethyl ester With sodium hydride in tetrahydrofuran
0.166667 h;
2: 2,5-dibromo-pyrimidine in tetrahydrofuran
T=20°C; 6 h;
3: With hydrogenchloride in water
参考文献
BAYER CROPSCIENCE SA
Patent: WO2006/117358 A1, 2006 ;
Location in patent: Page/Page column 37 ;
参考文献
Lapachev, V. V.; Zagulyeva, O. A.; Petrenko, O. P.; Bychkov, S. F.; Mamaev, V. P.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1984 , vol. 20, # 6 p. 676 - 680
Khimiya Geterotsiklicheskikh Soedinenii, 1984 , vol. 20, # 6 p. 827 - 831
