反应条件
1: 80 percent / LiAlH4 / tetrahydrofuran / 1) rt, overnight, 2) reflux, 8 h
2: 78 percent / PBr3, pyridine / diethyl ether / 1) rt, 2 h, 2) reflux, 2.5 h
3: 1) magnesium / 3) Li2CuCl4 / 1) THF, a) rt, b) 30 deg C, 3 h, 2) THF, - 5 deg C, 30 min, 3) a) -5 to -10 deg C, 4 h, b) overnight
4: 67 percent / p-toluenesulphonic acid / methanol / 2 h / Heating
View Scheme
参考文献
Vig, O. P.; Sharma, M. L.; Vohra, Neelam
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1986 , vol. 25, p. 1052 - 1053
