(1R,3R,4S,6S)-4,7,7-三甲基-4-({[(2-甲基-2-丙基)氧基]羰基}氨基)双环[4.1.0]庚烷-3-羧酸合成路线 （共 4 条）
反应条件
lithium hydroxide in tetrahydrofuran; water
T=20°C; 7 h;
参考文献
Gyonfalvi, Szilvia; Szakonyi, Zsolt; Fueloep, Ferenc
Tetrahedron Asymmetry, 2003 , vol. 14, # 24 p. 3965 - 3972
反应条件
1: 76 percent / diethyl ether / 9 h / 20 °C
2: 82 percent / Et3N; DMAP / tetrahydrofuran / 2 h / 20 °C
3: 94 percent / LiOH / tetrahydrofuran; H2O / 7 h / 20 °C
View Scheme
参考文献
Gyonfalvi, Szilvia; Szakonyi, Zsolt; Fueloep, Ferenc
Tetrahedron Asymmetry, 2003 , vol. 14, # 24 p. 3965 - 3972
反应条件
1: 82 percent / Et3N; DMAP / tetrahydrofuran / 2 h / 20 °C
2: 94 percent / LiOH / tetrahydrofuran; H2O / 7 h / 20 °C
View Scheme
参考文献
Gyonfalvi, Szilvia; Szakonyi, Zsolt; Fueloep, Ferenc
Tetrahedron Asymmetry, 2003 , vol. 14, # 24 p. 3965 - 3972
反应条件
1: 98 percent / diethyl ether / 1 h / 20 °C
2: 96 percent / trifluoroacetic acid / CH2Cl2 / 2 h / 0 °C
3: 85 percent / LiAlH4 / tetrahydrofuran / 2 h / 20 °C
View Scheme
参考文献
Gyonfalvi, Szilvia; Szakonyi, Zsolt; Fueloep, Ferenc
Tetrahedron Asymmetry, 2003 , vol. 14, # 24 p. 3965 - 3972
