1: 46 percent / KOH / dimethylformamide / 2 h / 0 °C 2: 65 percent / KOH, iodosobenzene diacetate / methanol / 1.) 0 deg C, 10 min, 2.) r.t., 16 h 3: aq. HCl / methanol View Scheme

1.1: sodium hydroxide / ethanol / 0.08 h / 20 °C 1.2: 24 h / 20 °C 2.1: dihydrogen peroxide / water / 24 h / 20 °C 3.1: hydrogenchloride; water / methanol / 0.5 h / Reflux View Scheme

1.1: 46 percent / potassium hydroxide / ethanol; H2O / 8 h / 20 °C 2.1: aq. HCl / methanol / 3 h / Heating 2.2: 37 percent / sodium acetate / methanol / 3 h View Scheme

1: 1.) NaOH, 2.) tetrabutylamonium chloride / 1.) CH2Cl2, water, RT, 15 min, 2.) CH2Cl2, water, RT, 16 h 2: 90 percent / KOH / ethanol / 15 h / Ambient temperature 3: 93 percent / 30percent aq. H2O2, 2 N NaOH / methanol / 19 h / Ambient temperature 4: 89 percent / HCl / methanol / 0.25 h / 50 °C View Scheme

1: 100 percent / K2CO3 / dimethylformamide / 3 h / 80 °C 2: 100 percent / HCl / methanol / 1 h / Heating 3: 84 percent / K2CO3 / dimethylformamide / 0 - 20 °C 4: 75 percent / 4 Angstroem molecular sieves; BF3*Et2O / CH2Cl2 / -78 - 20 °C 5: 100 percent / K2CO3 / dimethylformamide / 3 h / 80 °C 6: 40 percent / H2 / Pd/C / ethyl acetate / 2 h / 20 °C 7: 91 percent / NaOH / dioxane; H2O / 24 h / 20 °C 8: 76 percent / I2 / dimethylsulfoxide / 0.25 h / 200 °C 9: 100 percent / H2 / Pd/C / ethyl acetate; ethanol / 4.5 h / 20 °C View Scheme

1: potassium hydroxide / ethanol 2: sodium acetate / ethanol / Reflux 3: hydrogenchloride / methanol; water / 0.5 h / Reflux View Scheme

1: 46 percent / potassium hydroxide / ethanol; H2O / 8 h / 20 °C 2: aq. HCl / methanol / Heating View Scheme

1: 89 percent / KOH / ethanol; H2O / Ambient temperature 2: 80 percent / NaOAc / ethanol; H2O / 24 h / Heating 3: 92 percent / 3 N aq. HCl / methanol / 0.25 h / Heating View Scheme

1: potassium hydroxide / ethanol 2: sodium acetate / ethanol / Reflux 3: hydrogenchloride / methanol; water / 0.5 h / Reflux View Scheme

1: 2',4',6'-trihydroxyacetophenone With N-ethyl-N,N-diisopropylamine in dichloromethane T=0°C; Inert atmosphere; 2: chloromethyl methyl ether in dichloromethane T=0 - 20°C;