2,6-二甲氧基吡啶-3-甲酸甲酯合成路线 （共 8 条）
反应条件
sodium in methanol; benzene
反应条件
oxygen; potassium carbonate T=80°C; P=750.075 Torr; 24 h; Schlenk techniqueGreen chemistry;
参考文献
Jagadeesh, Rajenahally V.; Junge, Henrik; Pohl, Marga-Martina; Radnik, Joerg; Brueckner, Angelika; Beller, Matthias
Journal of the American Chemical Society, 2013 , vol. 135, # 29 p. 10776 - 10782
反应条件
1: 96 percent / conc. H2SO4 / 6 h / Heating 2: methanol / 4 h / 20 °C View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 48, # 12 p. 1847 - 1853
反应条件
1: 93 percent / conc. H2SO4 / 20 h / Heating 2: dimethylformamide / 0.17 h / 5 °C View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 48, # 12 p. 1847 - 1853
反应条件
in tetrahydrofuran T=5°C; 0.166667 h;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 48, # 12 p. 1847 - 1853
反应条件
in tetrahydrofuran T=20°C; 4 h;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 48, # 12 p. 1847 - 1853
反应条件
1: methanol; 2,6-dichloro-3-carboxypyridine With potassium tert-butylate T=60°C; 1 h; Microwave irradiation; 2: methanol With thionyl chloride T=0 - 20°C;
参考文献
Synlett, , # 2 art. no. S05610ST, p. 203 - 206
反应条件
lithium hexamethyldisilazane in tetrahydrofuran
T=-40°C; 0.333333 h; Inert atmosphere;
参考文献
Venkat Ragavan; Vijayakumar; Rajesh; Palakshi Reddy; Karthikeyan; Suchetha Kumari
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 12 p. 4193 - 4197
