6-氯-2-甲氧基烟酸甲酯合成路线 （共 8 条）
反应条件
in dichloromethane T=-5 - 20°C; 16 h;
参考文献
Boos, Charles; Bowles, Daniel M.; Cai, Cuiman; Casimiro-Garcia, Agustin; Chen, Xiangyang; Hulford, Catherine A.; Jennings, Sandra M.; Jason Kiser; Piotrowski, David W.; Sammons, Matthew; Wade, Robert A.
Tetrahedron Letters, 2011 , vol. 52, # 52 p. 7025 - 7029
反应条件
sodium methylate in methanol; dichloromethane T=20°C; 48 h;
参考文献
EP2085383 A1, ;
Page/Page column 22 ;
EP 2085383 A1
反应条件
1: 96 percent / conc. H2SO4 / 6 h / Heating 2: methanol / 4 h / 20 °C View Scheme
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 48, # 12 p. 1847 - 1853
反应条件
in tetrahydrofuran T=20°C; 4 h;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 48, # 12 p. 1847 - 1853
反应条件
in dichloromethane T=20°C; 4 h;
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 48, # 12 p. 1847 - 1853
反应条件
1: methanol; 2,6-dichloro-3-carboxypyridine With potassium tert-butylate T=60°C; 1 h; Microwave irradiation; 2: methanol With thionyl chloride T=0 - 20°C;
参考文献
Synlett, , # 2 art. no. S05610ST, p. 203 - 206
反应条件
in methanol; sodium hydroxide
参考文献
Ciba-Geigy Corporation
Patent: US4089960 A1, 1978 ;
