5-溴-5′-己基-2,2′-联噻吩合成路线 （共 9 条）
反应条件
N-bromosuccinmide in N,N-dimethyl-formamide
T=20°C; Darkness;
参考文献
Matsumoto, Kouzou; Kugo, Sota; Takajo, Daisuke; Inaba, Akira; Hirao, Yasukazu; Kurata, Hiroyuki; Kawase, Takeshi; Kubo, Takashi
Chemistry - An Asian Journal, 2012 , vol. 7, # 1 p. 225 - 232
反应条件
in N,N-dimethyl-formamide
T=85°C; 12 h;
参考文献
SFC CO., LTD.
Patent: US2012/247546 A1, 2012 ;
Location in patent: Page/Page column 37 ;
反应条件
1: NBS / tetrahydrofuran / 20 °C
2: Mg / Ni(dppp)Cl2 / diethyl ether / Heating
3: NBS / tetrahydrofuran / 20 °C
View Scheme
参考文献
Funahashi, Masahiro; Hanna, Jun-Ichi
Molecular Crystals and Liquid Crystals, 2004 , vol. 410, p. 1/[529]-12/[540]
反应条件
1: benzene / 0.25 h / 0 °C
2: 3.40 g / LiAlH4; AlCl3 / toluene; diethyl ether / 1 h / 20 °C
3: 94 percent / NBS / dimethylformamide / 0.5 h / 20 °C
View Scheme
参考文献
Nicolas, Yohann; Blanchard, Philippe; Levillain, Eric; Allain, Magali; Mercier, Nicolas; Roncali, Jean
Organic Letters, 2004 , vol. 6, # 2 p. 273 - 276
反应条件
1.1: n-butyllithium / tetrahydrofuran; hexane / 1.5 h / -60 - 0 °C / Inert atmosphere
1.2: -60 - 20 °C / Inert atmosphere
2.1: N-bromosuccinmide / N,N-dimethyl-formamide / 20 °C / Darkness
3.1: magnesium / diethyl ether / 4 h / Inert atmosphere; Reflux
3.2: 48 h / Inert atmosphere; Reflux
4.1: N-bromosuccinmide / N,N-dimethyl-formamide / 20 °C / Darkness
View Scheme
参考文献
Matsumoto, Kouzou; Kugo, Sota; Takajo, Daisuke; Inaba, Akira; Hirao, Yasukazu; Kurata, Hiroyuki; Kawase, Takeshi; Kubo, Takashi
Chemistry - An Asian Journal, 2012 , vol. 7, # 1 p. 225 - 232
反应条件
1: 75 percent / Ni(dppp)Cl2 / diethyl ether / Heating
2: 80 percent / NBS / tetrahydrofuran
View Scheme
参考文献
Funahashi, Masahiro; Hanna, Jun-Ichi
Molecular Crystals and Liquid Crystals, 2005 , vol. 436, p. 225/[1179]-235/[1189]
反应条件
1: benzene / 0.25 h / 0 °C
2: 3.40 g / LiAlH4; AlCl3 / toluene; diethyl ether / 1 h / 20 °C
3: 94 percent / NBS / dimethylformamide / 0.5 h / 20 °C
View Scheme
参考文献
Nicolas, Yohann; Blanchard, Philippe; Levillain, Eric; Allain, Magali; Mercier, Nicolas; Roncali, Jean
Organic Letters, 2004 , vol. 6, # 2 p. 273 - 276
反应条件
1: 3.40 g / LiAlH4; AlCl3 / toluene; diethyl ether / 1 h / 20 °C
2: 94 percent / NBS / dimethylformamide / 0.5 h / 20 °C
View Scheme
参考文献
Nicolas, Yohann; Blanchard, Philippe; Levillain, Eric; Allain, Magali; Mercier, Nicolas; Roncali, Jean
Organic Letters, 2004 , vol. 6, # 2 p. 273 - 276
反应条件
1.1: 75 percent / Ni(dppp)Cl2 / diethyl ether / Heating
2.1: nBuLi / tetrahydrofuran / -78 °C
2.2: I2 / tetrahydrofuran
View Scheme
参考文献
Funahashi, Masahiro; Hanna, Jun-Ichi
Molecular Crystals and Liquid Crystals, 2005 , vol. 436, p. 225/[1179]-235/[1189]
