N-苄氧羰基-3-氨基丙醛合成路线 （共 11 条）
反应条件
Dess-Martin periodane in dichloromethane T=20°C;
参考文献
DeMong, Duane E.; Williams, Robert M.
Tetrahedron Letters, 2001 , vol. 42, # 2 p. 183 - 185
反应条件
hydrogenchloride in acetone 1 h; Heating;
参考文献
Teshima, Tadashi; Konishi, Kunikazu; Shiba, Tetsuo
Bulletin of the Chemical Society of Japan, 1980 , vol. 53, # 2 p. 508 - 511
反应条件
1: With camphor-10-sulfonic acid 15 h; Heating; 2: With diisobutylaluminium hydride in hexane; dichloromethane T=-78°C; 2 h;
参考文献
Angewandte Chemie - International Edition, , vol. 40, # 5 p. 903 - 905
反应条件
1: aq. NaHCO3 / dioxane / 3.75 h / 0 - 20 °C 2: Et3N / tetrahydrofuran / 2 h / 0 °C 3: aq. sodium borohydride / tetrahydrofuran / 5 h / 0 °C 4: (COCl)2; DMSO / CH2Cl2 / 0.25 h / -78 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 121, # 49 p. 11356 - 11368
反应条件
1: aq. sodium borohydride / tetrahydrofuran / 5 h / 0 °C 2: (COCl)2; DMSO / CH2Cl2 / 0.25 h / -78 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 121, # 49 p. 11356 - 11368
反应条件
diisobutylaluminium hydride in toluene T=-78°C; Reduction;
参考文献
Tetrahedron Letters, , vol. 40, # 21 p. 4085 - 4088
反应条件
1: With oxalyl dichloride; triethylamine in dichloromethane; dimethyl sulfoxide T=-48°C; 75 h; 2: With oxalyl dichloride in dichloromethane; dimethyl sulfoxide T=-40 - -30°C;
参考文献
EP1170289 A2, ;
Page 56 ;
反应条件
1: 99 percent / triethylamine / methanol / 1 h / Heating 2: 98 percent / Dess-Martin periodinane / CH2Cl2 / 20 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 42, # 2 p. 183 - 185
反应条件
1: With sodium hydroxide T=0°C; 2: With oxalyl dichloride T=-78°C;
参考文献
European Journal of Medicinal Chemistry, , vol. 44, # 2 p. 670 - 677
参考文献
Angewandte Chemie, , vol. 95, # 8 p. 646 - 647
