1-(2-氟苯基)-2-硫脲合成路线 （共 11 条）
反应条件
ammonia in methanol 12 h;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 7 p. 915 - 918
反应条件
sodium hydroxide T=100°C;
参考文献
Gupta, K. A.; Saxena, Anil K.; Jain, Padam C.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, # 3 p. 228 - 233
反应条件
in water 4 h; Heating;
参考文献
Gupta, R. R.; Kumar, Rakesh
Synthetic Communications, 1987 , vol. 17, # 2 p. 229 - 240
反应条件
hydrogenchloride T=80°C; 12 h;
参考文献
Journal of Medicinal Chemistry, , vol. 51, # 5 p. 1242 - 1251
反应条件
1: aq. NaHCO3 / CHCl3 / 0.5 h 2: NH3 / methanol / 12 h View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 7 p. 915 - 918
反应条件
1: 78 percent / benzene 2: 88 percent / 2,5 N NaOH / 100 °C View Scheme
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 21, # 3 p. 228 - 233
反应条件
pyridine; hydrogen sulfide; triethylamine T=20°C; 72 h;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 20, # 3 p. 1177 - 1180
参考文献
Journal of the Chemical Society [Section] C: Organic, , p. 268 - 272
反应条件
1: With bromine in chloroform T=20°C; 3 h; Heating / reflux; 2: With ammonium hydroxide in water
参考文献
KINETEK PHARMACEUTICALS, INC.
Patent: WO2004/11460 A2, 2004 ;
Location in patent: Page 57 ;
WO 2004/011460 A2
反应条件
iodine; triethylamine in water; ethyl acetate
参考文献
Yella, Ramesh; Kavala, Veerababurao; Patel, Bhisma K.
Synthetic Communications, 2011 , vol. 41, # 6 p. 792 - 805
