1-(2-甲基苯基)-4-氧代环己烷甲腈合成路线 (共 2 条)
反应条件
sulfuric acid in acetic acid
24 h; Heating;
参考文献
Lednicer, Daniel; VonVoigtlander, Philip F.; Emmert, D. Edward
Journal of Medicinal Chemistry, 1980 , vol. 23, # 4 p. 424 - 430
反应条件
sulfuric acid; acetic acid in 5-cyano-2-oxo-5-o-tolyl-cyclohexanecarboxylic acid methyl ester
参考文献
The Upjohn Company
Patent: US4065573 A1, 1977 ;