1: 54 percent / p-toluenesulfonic acid / benzene / 4.6 h / Heating 2: 88 percent / CrO3, 3,5-dimethylpyrazole / CH2Cl2 / 0.17 h 3: 84 percent / H2O; methanol / 48 h / Ambient temperature 4: 1.) Mg / 1.) THF, 2.) THF, reflux, 24 h 5: etheral HCl View Scheme

1: 54 percent / p-toluenesulfonic acid / benzene / 4.6 h / Heating 2: 88 percent / CrO3, 3,5-dimethylpyrazole / CH2Cl2 / 0.17 h 3: 84 percent / H2O; methanol / 48 h / Ambient temperature 4: 1.) Mg / 1.) THF, 2.) THF, reflux, 24 h 5: etheral HCl View Scheme

1: 84 percent / H2O; methanol / 48 h / Ambient temperature 2: 1.) Mg / 1.) THF, 2.) THF, reflux, 24 h 3: etheral HCl View Scheme

1: 88 percent / CrO3, 3,5-dimethylpyrazole / CH2Cl2 / 0.17 h 2: 84 percent / H2O; methanol / 48 h / Ambient temperature 3: 1.) Mg / 1.) THF, 2.) THF, reflux, 24 h 4: etheral HCl View Scheme

1: 1.) Mg / 1.) THF, 2.) THF, reflux, 24 h 2: etheral HCl View Scheme

1: p-toluenesulfonic acid / 4 h / Ambient temperature 2: 1.) Mg / 1.) THF, 2.) THF, reflux, 24 h 3: etheral HCl View Scheme

1: 1.) Mg / 1.) THF, 2.) THF, reflux, 24 h 2: etheral HCl View Scheme