N-(四氢-2H-吡喃-4-基)-4-(4,4,5,5-四甲基-1,3,2-二噁硼烷-2-基)苯甲酰胺合成路线 （共 2 条）
反应条件
1: 4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzoic acid With thionyl chloride
2 h; Heating / reflux;
2: tetrahydro-pyran-4-yl-amine With triethylamine in dichloromethane; toluene
T=10 - 20°C; 48 h;
参考文献
SMITHKLINE BEECHAM CORPORATION
Patent: WO2004/13138 A2, 2004 ;
Location in patent: Page 24 ;
WO 2004/013138 A2
反应条件
triethylamine in dichloromethane; toluene
T=10 - 20°C; 48 h;
参考文献
SMITHKLINE BEECHAM CORPORATION
Patent: WO2004/13125 A1, 2004 ;
Location in patent: Page 20 ;
WO 2004/013125 A1
