(Z)-十四-5-烯基溴化物合成路线 （共 5 条）
反应条件
phosphorus tribromide in dichloromethane
T=0 - 20°C; 15 h;
参考文献
Verniest, Guido; Boterberg, Stefaan; Colpaert, Jeroen; Van Thienen, Tinneke; Stevens, Christian V.; De Kimpe, Norbert
Synlett, 2004 , # 7 p. 1273 - 1275
反应条件
1: liq. NH3, NaNH2
2: H2 / Lindlar catalyst / methanol
View Scheme
参考文献
MacConnell,J.G. et al.
Tetrahedron, 1971 , vol. 27, p. 1129 - 1139
反应条件
1.1: BuLi / tetrahydrofuran; hexamethylphosphoric acid triamide / 3 h / -10 - 20 °C
1.2: 62 percent / tetrahydrofuran; hexamethylphosphoric acid triamide
2.1: 95 percent / H2; Lindlar catalyst; quinoline / pentane / 0.17 h / 0 °C / 3750.3 Torr
3.1: 57 percent / PBr3 / CH2Cl2 / 15 h / 0 - 20 °C
View Scheme
参考文献
Verniest, Guido; Boterberg, Stefaan; Colpaert, Jeroen; Van Thienen, Tinneke; Stevens, Christian V.; De Kimpe, Norbert
Synlett, 2004 , # 7 p. 1273 - 1275
反应条件
1.1: BuLi / tetrahydrofuran; hexamethylphosphoric acid triamide / 3 h / -10 - 20 °C
1.2: 62 percent / tetrahydrofuran; hexamethylphosphoric acid triamide
2.1: 95 percent / H2; Lindlar catalyst; quinoline / pentane / 0.17 h / 0 °C / 3750.3 Torr
3.1: 57 percent / PBr3 / CH2Cl2 / 15 h / 0 - 20 °C
View Scheme
参考文献
Verniest, Guido; Boterberg, Stefaan; Colpaert, Jeroen; Van Thienen, Tinneke; Stevens, Christian V.; De Kimpe, Norbert
Synlett, 2004 , # 7 p. 1273 - 1275
反应条件
1: 95 percent / H2; Lindlar catalyst; quinoline / pentane / 0.17 h / 0 °C / 3750.3 Torr
2: 57 percent / PBr3 / CH2Cl2 / 15 h / 0 - 20 °C
View Scheme
参考文献
Verniest, Guido; Boterberg, Stefaan; Colpaert, Jeroen; Van Thienen, Tinneke; Stevens, Christian V.; De Kimpe, Norbert
Synlett, 2004 , # 7 p. 1273 - 1275
