4-(2-吡咯烷乙氧基)苯硼酸频那醇酯合成路线 (共 2 条)
反应条件
potassium acetate; 1,1'-bis-(diphenylphosphino)ferrocene; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct in dimethyl sulfoxide
T=80°C; 20 h;
参考文献
ASTRAZENECA AB; ASTRAZENECA UK LIMITED
Patent: WO2008/84223 A2, 2008 ;
Location in patent: Page/Page column 157 ;
WO 2008/084223 A2
反应条件
triethylamine; bis-triphenylphosphine-palladium(II) chloride in 1,4-dioxane
4 h; Heating / reflux;
参考文献
SMITHKLINE BEECHAM CORPORATION
Patent: WO2004/13125 A1, 2004 ;
Location in patent: Page 20-21 ;
WO 2004/013125 A1