lithium aluminium tetrahydride in tetrahydrofuran T=70 - 75°C; 8 h;

1: 95.6 percent / LiAlH4 / tetrahydrofuran / 8 h / 70 - 75 °C 2: CHCl3 / 0.5 h / Ambient temperature View Scheme

1: 95.6 percent / LiAlH4 / tetrahydrofuran / 8 h / 70 - 75 °C 2: 82.4 percent / P4O10 / CHCl3 / 1 h / Ambient temperature View Scheme

<b>Multi-step reaction with 3 steps<br /> </b>1: 80 percent / NEt₃ / CH₂Cl₂ / 0 &deg;C<br />2: 75 percent / NEt₃ / toluene / 24 h / 110 &deg;C<br />3: 52 percent / K₂CO₃; H₂O / methanol / 0.5 h / 20 &deg;C<br /> <br /> &nbsp;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '3587155', constants.ctx, '0')">water</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '605283', constants.ctx, '0')">triethylamine</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '741857', constants.ctx, '0')">acetonitrile</a> <br /> <br /> &nbsp;

<b>Multi-step reaction with 4 steps<br /> </b>1: 91 percent / NEt₃ / CH₂Cl₂ / 1 h / 20 &deg;C<br />2: 80 percent / NEt₃ / CH₂Cl₂ / 0 &deg;C<br />3: 75 percent / NEt₃ / toluene / 24 h / 110 &deg;C<br />4: 52 percent / K₂CO₃; H₂O / methanol / 0.5 h / 20 &deg;C<br /> <br /> &nbsp;

&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1718733', constants.ctx, '0')">ethanol</a> <br />144&nbsp;h;&nbsp;&nbsp;Ambient temperature;&nbsp;<br /> &nbsp;

&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '635760', constants.ctx, '0')">toluene</a> <br />T=20&deg;C;&nbsp;Condensation;&nbsp;18&nbsp;h;&nbsp;<br /> &nbsp;