5-溴苯并[d]异噁唑-3(2H)-酮合成路线 （共 2 条）
反应条件
1: With thionyl chloride in tetrahydrofuran
T=10 - 20°C; 2 h;
2: With triethylamine in 1,4-dioxane
T=0 - 20°C;
参考文献
PHENEX PHARMACEUTICALS AG; KREMOSER, Claus; ABEL, Ulrich; STEENECK, Christoph; KINZEL, Olaf
Patent: WO2011/20615 A1, 2011 ;
Location in patent: Page/Page column 75; 76 ;
反应条件
bromine in acetic acid
0.25 h; Heating;
参考文献
Wrubel, Juergen
Zeitschrift fuer Chemie (Stuttgart, Germany), 1980 , vol. 20, # 1 p. 18
