1-溴-4,4-二甲基戊烷合成路线 （共 16 条）
反应条件
1.1: Mg / diethyl ether / 2 h / 20 °C
1.2: 43.9 percent / diethyl ether / 1 h / 20 °C
2.1: 44.8 percent / LiAlH4 / diethyl ether / 5 h / Heating
3.1: 54.4 percent / PBr3; pyridine / 12 h / Heating
View Scheme
参考文献
Hamano, Hiroshi; Nagata, Keiichi; Fukada, Nobuo; Shimotahira, Hiroshi; Ju, Xiu-Lian; Ozoe, Yoshihisa
Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 3 p. 665 - 674
反应条件
1.1: 99.2 percent / PBr3; pyridine / 12 h / Heating
2.1: Mg / diethyl ether / 2 h / 20 °C
2.2: 43.9 percent / diethyl ether / 1 h / 20 °C
3.1: 44.8 percent / LiAlH4 / diethyl ether / 5 h / Heating
4.1: 54.4 percent / PBr3; pyridine / 12 h / Heating
View Scheme
参考文献
Hamano, Hiroshi; Nagata, Keiichi; Fukada, Nobuo; Shimotahira, Hiroshi; Ju, Xiu-Lian; Ozoe, Yoshihisa
Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 3 p. 665 - 674
反应条件
1: 44.8 percent / LiAlH4 / diethyl ether / 5 h / Heating
2: 54.4 percent / PBr3; pyridine / 12 h / Heating
View Scheme
参考文献
Hamano, Hiroshi; Nagata, Keiichi; Fukada, Nobuo; Shimotahira, Hiroshi; Ju, Xiu-Lian; Ozoe, Yoshihisa
Bioorganic and Medicinal Chemistry, 2000 , vol. 8, # 3 p. 665 - 674
参考文献
Whitmore; Homeyer
Journal of the American Chemical Society, 1933 , vol. 55, p. 4558
Full Text Show Details
Kharasch; Hannum; Gladstone
Journal of the American Chemical Society, 1934 , vol. 56, p. 244
反应条件
1: 70 percent / Na/C2H5OH / 6 h / Heating
3: 84 percent / LiAlH4 / diethyl ether
View Scheme
参考文献
Schulz; Sprung; Kroning
Pharmazie, 1983 , vol. 38, # 5 p. 310 - 313
反应条件
1: 70 percent / Na/C2H5OH / 6 h / Heating
3: 84 percent / LiAlH4 / diethyl ether
4: 90 percent
View Scheme
参考文献
Schulz; Sprung; Kroning
Pharmazie, 1983 , vol. 38, # 5 p. 310 - 313
