N-叔丁氧羰基-3-[(苄氧羰基)氨基]-L-丙氨酸合成路线 （共 22 条）
反应条件
1: 95 percent / CuCl / dimethylformamide / 1 h 2: 10 percent / NaOH / methanol; H2O / 2 h View Scheme
参考文献
Organic Letters, , vol. 6, # 2 p. 213 - 215
反应条件
1: 2.52 g / toluene / 2 h / Heating 2: 95 percent / CuCl / dimethylformamide / 1 h 3: 10 percent / NaOH / methanol; H2O / 2 h View Scheme
参考文献
Organic Letters, , vol. 6, # 2 p. 213 - 215
反应条件
triethylamine in 1,4-dioxane; water
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 33, # 2 p. 509 - 514
反应条件
1: 2.4 g / CuCl / dimethylformamide / 20 °C 2: 92 percent / NaOH / methanol / 20 °C View Scheme
参考文献
Synthetic Communications, , vol. 36, # 24 p. 3803 - 3807
反应条件
1: ethyl chloroformate; N-methylmorpholine; aq. sodium azide / tetrahydrofuran / 1 h / -10 °C 2: toluene / 75 °C 3: 2.4 g / CuCl / dimethylformamide / 20 °C 4: 92 percent / NaOH / methanol / 20 °C View Scheme
参考文献
Synthetic Communications, , vol. 36, # 24 p. 3803 - 3807
反应条件
1: toluene / 75 °C 2: 2.4 g / CuCl / dimethylformamide / 20 °C 3: 92 percent / NaOH / methanol / 20 °C View Scheme
参考文献
Synthetic Communications, , vol. 36, # 24 p. 3803 - 3807
反应条件
1: 1.) SOCl2 / 1.) ether, a) r.t., 90 min., b) reflux, 3 h, 2.) r.t., overnight 2: 86.07 percent / Et3N / dimethylformamide / Ambient temperature 3: 84.4 percent / 1N NaOH / methanol / 1 h View Scheme
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 21, # 5 p. 483 - 484
反应条件
1: 86.07 percent / Et3N / dimethylformamide / Ambient temperature 2: 84.4 percent / 1N NaOH / methanol / 1 h View Scheme
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 21, # 5 p. 483 - 484
反应条件
pyridine; sodium hydrogencarbonate; bis-[(trifluoroacetoxy)iodo]benzene 1.) dioxane, water; Yield given. Multistep reaction;
参考文献
Tetrahedron Letters, , vol. 33, # 30 p. 4275 - 4278
参考文献
Chemical and Pharmaceutical Bulletin, , vol. 53, # 9 p. 1152 - 1158
