4-(5-硝基嘧啶-2-基)吗啉合成路线 （共 4 条）
反应条件
N-ethyl-N,N-diisopropylamine in acetonitrile
T=20°C; 72 h;
参考文献
MEDICAL RESEARCH COUNCIL
Patent: WO2009/122180 A1, 2009 ;
Location in patent: Page/Page column 95-96 ;
WO 2009/122180 A1
反应条件
triethylamine in dichloromethane
T=23°C; 3 h;
参考文献
Yun, Weiya; Ahmad, Mushtaq; Chen, Yingsi; Gillespie, Paul; Conde-Knape, Karin; Kazmer, Sonja; Li, Shiming; Qian, Yimin; Taub, Rebecca; Wertheimer, Stanley J.; Whittard, Toni; Bolin, David
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 23 p. 7205 - 7209
参考文献
Hurst,D.T.; Christophides,J.
Heterocycles, 1977 , vol. 6, p. 1999 - 2004
反应条件
hydrazine hydrate; palladium on activated charcoal
参考文献
Yun, Weiya; Ahmad, Mushtaq; Chen, Yingsi; Gillespie, Paul; Conde-Knape, Karin; Kazmer, Sonja; Li, Shiming; Qian, Yimin; Taub, Rebecca; Wertheimer, Stanley J.; Whittard, Toni; Bolin, David
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 23 p. 7205 - 7209
