5-(3-氯苯基)-异噁唑-3-羧酸乙酯合成路线 （共 11 条）
反应条件
1: With triethylamine in tetrahydrofuran; diethyl ether; toluene
T=0°C; 5 h;
2: With hydrogenchloride; water in tetrahydrofuran; diethyl ether; toluene
3: With methanol; potassium hydroxide; water
T=45°C; 0.5 h;
参考文献
AstraZeneca AB; NPS PHARMACEUTICALS, INC.
Patent: US2007/259895 A1, 2007 ;
Location in patent: Page/Page column 10 ;
US 20070259895 A1
