1: NaOH / methanol / 12 h / Heating 2: 98 percent / H2; acetic acid / 10 percent Pd/C / 3 h / 75 °C View Scheme

1: NaOH / methanol / 12 h / Heating 2: 10 percent / H2; acetic acid / 10 percent Pd/C / 3 h / 75 °C View Scheme

hydrogen; triethylamine; Ru2Cl4((R)-(+)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl)2 in tetrahydrofuran; toluene T=35°C; P=2206.5 Torr; 48 h; var. cat. RuHCl*2<(+)-BINAP>;

1: NaOH / methanol / 12 h / Heating 2: 10 percent / H2; acetic acid / 10 percent Pd/C / 3 h / 75 °C View Scheme

1: NaOH / methanol / 12 h / Heating 2: 10 percent / H2; acetic acid / 10 percent Pd/C / 3 h / 75 °C 3: H2SO4 / 8 h / 20 °C View Scheme

1: NaOH / methanol / 12 h / Heating 2: 98 percent / H2; acetic acid / 10 percent Pd/C / 3 h / 75 °C 3: 73 percent / H2SO4 / 8 h / 20 °C View Scheme

1: NaOH / methanol / 12 h / Heating 2: 98 percent / H2; acetic acid / 10 percent Pd/C / 3 h / 75 °C 3: 73 percent / H2SO4 / 8 h / 20 °C 4: 93 percent / diethyl ether 5: 85 percent / LiAlH4 / tetrahydrofuran / 12 h / 20 °C 6: 75 percent / MnO2 / CHCl3 / 4 h / 20 °C View Scheme

1: NaOH / methanol / 12 h / Heating 2: 98 percent / H2; acetic acid / 10 percent Pd/C / 3 h / 75 °C 3: 73 percent / H2SO4 / 8 h / 20 °C 4: 93 percent / diethyl ether View Scheme