1-氧代-1,2-二氢异喹啉-7-羧酸甲酯合成路线 (共 2 条)
反应条件
triethylamine; 1,3-bis-(diphenylphosphino)propane; palladium diacetate in dimethyl sulfoxide
T=70°C; P=760.051 Torr; 18 h; Inert atmosphere;
参考文献
Millennium Pharmaceuticals, Inc.
Patent: US2012/94997 A1, 2012 ;
Location in patent: Page/Page column 75 ;
US 20120094997 A1
反应条件
triethylamine; 1,1'-bis(diphenylphosphino)ferrocene in methanol
T=100°C; 20 h;
参考文献
WARNER-LAMBERT COMPANY LLC
Patent: WO2004/14379 A1, 2004 ;
Location in patent: Page/Page column 112 ;
WO 2004/014379 A1