N-(2-溴苯基)-2,2-二甲基丙酰胺合成路线 （共 14 条）
反应条件
1: triethylamine / dichloromethane / 0 - 20 °C
2: N-bromosuccinmide; palladium diacetate; toluene-4-sulfonic acid / toluene / 4 h / 20 °C
View Scheme
参考文献
Bedford, Robin B.; Haddow, Mairi F.; Mitchell, Charlotte J.; Webster, Ruth L.
Angewandte Chemie - International Edition, 2011 , vol. 50, # 24 p. 5524 - 5527
反应条件
copper diacetate; palladium diacetate; copper(ll) bromide
T=120°C; Neat (no solvent);
参考文献
Bedford, Robin B.; Engelhart, Jens U.; Haddow, Mairi F.; Mitchell, Charlotte J.; Webster, Ruth L.
Dalton Transactions, 2010 , vol. 39, # 43 p. 10464 - 10472
反应条件
1: 70 percent / Lawesson reagent
2: 88 percent / Cs2CO3 / o-biphenylP(t-Bu)2; Pd2dba3 / dioxane / 18 h / 80 °C
View Scheme
参考文献
Gade, Thomas; Streek, Michael; Voss, Juergen
Chemische Berichte, 1992 , vol. 125, # 1 p. 127 - 142
反应条件
palladium diacetate; caesium carbonate; tris-(o-tolyl)phosphine; 2,2,2-trimethylacetic acid in 1-methyl-pyrrolidin-2-one
T=140°C; 48 h; Schlenk technique;
参考文献
Yan, Jia-Xuan; Li, Hu; Liu, Xiang-Wei; Shi, Jiang-Ling; Wang, Xin; Shi, Zhang-Jie
Angewandte Chemie - International Edition, 2014 , vol. 53, # 19 p. 4945 - 4949
