乙基3-氯-2-氧代丙酸酯合成路线 （共 6 条）
反应条件
1.) ether, HMPT, reflux, 3 h, 2.) EtOH, reflux, 1 h; Yield given. Multistep reaction;
参考文献
Sablayrolles; Cros; Milhavet; Rechenq; Chapat; Boucard; Serrano; McNeill
Journal of Medicinal Chemistry, 1984 , vol. 27, # 2 p. 206 - 212
反应条件
in ethanol Cyclization; Heating;
参考文献
Kim, Hwa-Ok; Kahn, Michael
Synlett, 1999 , # 8 p. 1239 - 1240
反应条件
in 1,4-dioxane
T=65°C; 0.5 h;
参考文献
Bredikhina, Z. A.; Buzykin, B. I.; Kitaev, Yu. P.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1991 , vol. 27, # 4 p. 427 - 433
Khimiya Geterotsiklicheskikh Soedinenii, 1991 , # 4 p. 537 - 543
反应条件
1.) DMC, reflux, 3 h, 2.) EtOH, reflux, 1 h; Yield given. Multistep reaction;
参考文献
Sablayrolles; Cros; Milhavet; Rechenq; Chapat; Boucard; Serrano; McNeill
Journal of Medicinal Chemistry, 1984 , vol. 27, # 2 p. 206 - 212
反应条件
1: 1.) ether, HMPT, reflux, 3 h, 2.) EtOH, reflux, 1 h
2: 67 percent / Br2 / ethanol / 1 h / Heating
View Scheme
参考文献
Sablayrolles; Cros; Milhavet; Rechenq; Chapat; Boucard; Serrano; McNeill
Journal of Medicinal Chemistry, 1984 , vol. 27, # 2 p. 206 - 212
参考文献
Dawson; Newbold; Spring
Journal of the Chemical Society, 1949 , p. 2579,2581
