甲基(2R,3S)-2,3-二羟基-3-苯丙酸酯合成路线 （共 6 条）
反应条件
4-methylmorpholine N-oxide; polyaniline-supported Os in water; acetone; acetonitrile
T=20°C;
参考文献
Choudary, Boyapati M.; Roy, Moumita; Roy, Sarabindu; Kantam, M. Lakshmi; Sreedhar, Bojja; Kumar, Karasala Vijay
Advanced Synthesis and Catalysis, 2006 , vol. 348, # 12-13 p. 1734 - 1742
反应条件
sodium tetrahydroborate in dichloromethane
T=-72 - 20°C; optical yield given as percent dediastereoselective reaction;
参考文献
Paioti, Paulo H.S.; Coelho, Fernando
Tetrahedron Letters, 2011 , vol. 52, # 46 p. 6180 - 6184
反应条件
potassium tert-butylate; (η5-C5Ph5)Ru(CO)2Cl in tetrahydrofuran; toluene
T=80°C; 1 h;
参考文献
Edin, Michaela; Martin-Matute, Belen; Baeckvall, Jan-E.
Tetrahedron Asymmetry, 2006 , vol. 17, # 4 p. 708 - 715
反应条件
camphor-10-sulfonic acid in ethylene glycol
4 h; Heating;
参考文献
Fujita, Morifumi; Laine, Dramane; Ley, Steven V.
Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 12 p. 1647 - 1656
反应条件
1: potassium bis(trimethylsilyl)amide / tetrahydrofuran
2: 63 percent / BCl3 / CH2Cl2
View Scheme
参考文献
Yamazaki, Takashi; Ando, Makoto; Kitazume, Tomoya; Kubota, Toshio; Omura, Masao
Organic Letters, 1999 , vol. 1, # 6 p. 905 - 908
反应条件
1.1: ozone / methanol / 1 h / -72 °C
1.2: 1 h / -72 °C
2.1: sodium tetrahydroborate / dichloromethane / -72 - 20 °C
View Scheme
参考文献
Paioti, Paulo H.S.; Coelho, Fernando
Tetrahedron Letters, 2011 , vol. 52, # 46 p. 6180 - 6184
