6-甲氧基-3-吡啶甲醛合成路线 （共 32 条）
反应条件
1: 2-bromo-propionic acid With phosphorous acid diethyl ester; sodium hydride in various solvent(s)
T=20°C; 0.5 h;
2: 6-(methoxy)-pyrid-3-yl-carboxaldehyde in various solvent(s)
T=20°C; Wittig-Horner olefination; 2 h;
参考文献
Baenziger, Markus; Cercus, Jacques; Hirt, Hans; Laumen, Kurt; Malan, Christophe; Spindler, Felix; Struber, Fritz; Troxler, Thomas
Tetrahedron Asymmetry, 2003 , vol. 14, # 22 p. 3469 - 3477
反应条件
1.1: sodium hydride; diethylphosphite / various solvent(s) / 0.5 h / 20 °C
1.2: 78 percent / various solvent(s) / 2 h / 20 °C
2.1: 89 percent / LiAlH4 / tetrahydrofuran / 3 h / 0 °C
View Scheme
参考文献
Baenziger, Markus; Cercus, Jacques; Hirt, Hans; Laumen, Kurt; Malan, Christophe; Spindler, Felix; Struber, Fritz; Troxler, Thomas
Tetrahedron Asymmetry, 2003 , vol. 14, # 22 p. 3469 - 3477
