甲基3-甲酰基-1-甲基-1H-吲哚-4-羧酸酯合成路线 （共 2 条）
反应条件
1: N,N-dimethyl-formamide With trichlorophosphate
T=0°C; Vilsmeier Formylation; Cooling with ice;
2: methyl 1-methyl-1H-indole-4-carboxylate Vilsmeier Formylation; 6 h;
3: With sodium hydroxide in water
Vilsmeier Formylation; pH=7; Cooling with ice;
参考文献
Albany Molecular Research, Inc.
Patent: US2009/298809 A1, 2009 ;
Location in patent: Page/Page column 14; 32 ;
US 20090298809 A1
反应条件
sodium hydride in N,N-dimethyl-formamide
T=0 - 20°C;
参考文献
Tripathy, Rabindranath; Ghose, Arup; Singh, Jasbir; Bacon, Edward R.; Angeles, Thelma S.; Yang, Shi X.; Albom, Mark S.; Aimone, Lisa D.; Herman, Joseph L.; Mallamo, John P.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 6 p. 1793 - 1798
