2-(4-甲基苯基)咪唑并[1,2-a]吡啶合成路线 (共 21 条)
反应条件
in dimethylsulfoxide-d6 18 h;
参考文献
Tetrahedron, , vol. 38, # 1 p. 49 - 56
反应条件
1,10-phenanthroline; copper (II) acetate monohydrate; zinc(II) iodide in 1,2-dichloro-benzene T=120°C; 24 h;
参考文献
Advanced Synthesis and Catalysis, , vol. 355, # 9 p. 1741 - 1747
反应条件
silver carbonate in 1,4-dioxane T=110°C; 10 h; Inert atmosphere;
参考文献
Chemical Communications (Cambridge, United Kingdom), , vol. 48, # 90 p. 11073 - 11075,3
Chemical Communications, , vol. 48, # 90 p. 11073 - 11075
反应条件
sodium carbonate in [emim]OTs T=20°C; 0.5 h;
参考文献
Journal of the Chinese Chemical Society, , vol. 57, # 2 p. 153 - 156
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in N,N-dimethyl-formamide T=115°C; 16 h;
参考文献
Journal of Organic Chemistry, , vol. 65, # 26 p. 9201 - 9205
反应条件
copper(II) bis(trifluoromethanesulfonate) in 1,2-dichloro-ethane T=80°C; 3 h;
参考文献
Tetrahedron Letters, , vol. 48, # 43 p. 7717 - 7720
反应条件
copper(l) iodide; oxygen in N,N-dimethyl-formamide T=110°C; P=760.051 Torr; 36 h; Schlenk techniqueSealed tubeGreen chemistry;
参考文献
Chemistry - A European Journal, , vol. 19, # 49 p. 16804 - 16808
反应条件
anhydrous iron chloride in N,N-dimethyl-formamide T=80°C; Michael Addition; 2 h;
参考文献
Advanced Synthesis and Catalysis, , vol. 355, # 6 p. 1065 - 1070
反应条件
1: 2-aminopyridine With potassium carbonate in o-di-fluorobenzene 0.75 h; DarknessInert atmosphere; 2: C15H12I(1+)*C2F3O2(1-) in o-di-fluorobenzene T=20°C; DarknessInert atmosphere; Concentration; Overall yield = 66 percent; regioselective reaction;
参考文献
Organic and Biomolecular Chemistry, , vol. 11, # 35 p. 5877 - 5884
反应条件
1: 71 percent / acetonitrile / Heating 2: 72 percent / DBU / dimethylformamide / 16 h / 115 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 65, # 26 p. 9201 - 9205