2-(4-甲基苯基)咪唑并[1,2-a]吡啶合成路线 （共 21 条）
反应条件
1: 71 percent / acetonitrile / Heating 2: 72 percent / DBU / dimethylformamide / 16 h / 115 °C View Scheme
参考文献
Journal of Organic Chemistry, , vol. 65, # 26 p. 9201 - 9205
反应条件
anhydrous iron chloride; tetra-(n-butyl)ammonium iodide T=90°C; 4 h;
参考文献
European Journal of Organic Chemistry, , vol. 2014, # 13 p. 2754 - 2763
反应条件
potassium carbonate T=150°C; 16 h;
参考文献
Journal of Organic Chemistry, , vol. 65, # 26 p. 9201 - 9205
反应条件
1: iodobenzene; 3-chloro-benzenecarboperoxoic acid / [emim]OTs / 1 h / 80 °C 2: sodium carbonate / [emim]OTs / 0.5 h / 20 °C View Scheme
参考文献
Journal of the Chinese Chemical Society, , vol. 57, # 2 p. 153 - 156
反应条件
ammonium acetate T=180°C; 0.0666667 h; Microwave irradiationneat (no solvent);
参考文献
Synlett, , # 11 p. 1606 - 1608
反应条件
1: acetone / |Reflux 2: hydrogenchloride / water / 1 h / |Reflux View Scheme
参考文献
ChemMedChem, , vol. 8, # 12 p. 2015 - 2025
反应条件
potassium carbonate in acetonitrile 10 h; Inert atmosphereRefluxsolid phase reaction;
参考文献
Journal of Chemical Research, , # 5 p. 289 - 291
反应条件
1: 0.02 h / 100 °C / Microwave irradiation; Neat (no solvent) 2: thiourea / 150 °C / Microwave irradiation; Neat (no solvent) View Scheme
参考文献
E-Journal of Chemistry, , vol. 9, # 3 p. 1047 - 1052
反应条件
1: N,N-dimethyl-formamide With trichlorophosphate in chloroform T=0 - 5°C; Vilsmeier-Haack Formylation; 2: 2-p-tolylimidazo[1,2-a]pyridine in chloroform T=20°C; Vilsmeier-Haack Formylation; Reflux;
参考文献
Kamal, Ahmed; Reddy, Vangala Santhosh; Karnewar, Santosh; Chourasiya, Sumit S.; Shaik, Anver Basha; Kumar, G. Bharath; Kishor, Chandan; Reddy, M. Kashi; Narasimha Rao; Nagabhushana, Ananthamurthy; Ramakrishna, Kallaganti V. S.; Addlagatta, Anthony; Kotamraju, Srigiridhar
ChemMedChem, 2013 , vol. 8, # 12 p. 2015 - 2025
参考文献
Almirante,L. et al.
Journal of Medicinal Chemistry, 1965 , vol. 8, p. 305 - 312
