2-氟-4-碘-5-氯吡啶合成路线 （共 3 条）
反应条件
1: With lithium diisopropyl amide T=-78°C; 7 h; 2: With iodine 2 h;
参考文献
WO2007/16358 A1, ;
Page/Page column 38 ;
反应条件
in dimethyl sulfoxide
T=150°C; 0.166667 h; microwave irradiation; Product distribution / selectivity;
参考文献
VERTEX PHARMACEUTICALS, INCORPORATED
Patent: WO2005/113541 A1, 2005 ;
Location in patent: Paragraph 0089 ;
WO 2005/113541 A1
反应条件
in N,N-dimethyl-formamide
T=150°C; 3 h; Microwave irradiation;
参考文献
MERCK and CO., INC.
Patent: WO2007/16358 A1, 2007 ;
Location in patent: Page/Page column 38-39 ;
