1.1: N,N-dimethyl-formamide / 20 h / 70 °C / |Inert atmosphere 1.2: 24 h / 70 °C / |Inert atmosphere 2.1: toluene / 2 h / |Inert atmosphere View Scheme

1.1: iodine; magnesium / tetrahydrofuran / 0 °C / |Reflux; |Inert atmosphere 1.2: 10 - 20 °C / |Inert atmosphere 2.1: sodium hydroxide / water; methanol / 20 °C / |Inert atmosphere 3.1: N,N-dimethyl-formamide / 20 h / 70 °C / |Inert atmosphere 3.2: 24 h / 70 °C / |Inert atmosphere 4.1: toluene / 2 h / |Inert atmosphere View Scheme

1.1: sodium hydroxide / water; methanol / 20 °C / |Inert atmosphere 2.1: N,N-dimethyl-formamide / 20 h / 70 °C / |Inert atmosphere 2.2: 24 h / 70 °C / |Inert atmosphere 3.1: toluene / 2 h / |Inert atmosphere View Scheme

1: 1,1'-carbonyldiimidazole / N,N-dimethyl-formamide / 19 h / 18 - 60 °C / |Inert atmosphere 2: toluene / 2 h / |Inert atmosphere View Scheme

in toluene 2 h; Inert atmosphere;