1H-吡咯并[3,2-d]嘧啶-2,4(3H,5H)-二酮合成路线 （共 14 条）
反应条件
1: 60.6 percent / POCl3 / 6 h / Heating 2: 18 percent / POCl3, diethylaniline / 40 h / Heating 3: 66.3 percent / potassium carbonate / aq. ethanol / 9 h / Heating View Scheme
参考文献
Modnikova, G. A.; Titkova, R. M.; Glushkov, R. G.; Sokolova, A. S.; Silin, V. A.; Chernov, V. A.
Pharmaceutical Chemistry Journal, 1988 , vol. 22, # 2 p. 135 - 141
Khimiko-Farmatsevticheskii Zhurnal, 1988 , vol. 22, # 2 p. 185 - 191
反应条件
1: 60.6 percent / POCl3 / 6 h / Heating 2: 18 percent / POCl3, diethylaniline / 40 h / Heating 3: 73.25 percent / potassium carbonate / H2O / 4 h / Heating View Scheme
参考文献
Modnikova, G. A.; Titkova, R. M.; Glushkov, R. G.; Sokolova, A. S.; Silin, V. A.; Chernov, V. A.
Pharmaceutical Chemistry Journal, 1988 , vol. 22, # 2 p. 135 - 141
Khimiko-Farmatsevticheskii Zhurnal, 1988 , vol. 22, # 2 p. 185 - 191
反应条件
1: 60.6 percent / POCl3 / 6 h / Heating 2: 18 percent / POCl3, diethylaniline / 40 h / Heating 3: potassium carbonate / aq. ethanol / 4 h / Heating View Scheme
参考文献
Modnikova, G. A.; Titkova, R. M.; Glushkov, R. G.; Sokolova, A. S.; Silin, V. A.; Chernov, V. A.
Pharmaceutical Chemistry Journal, 1988 , vol. 22, # 2 p. 135 - 141
Khimiko-Farmatsevticheskii Zhurnal, 1988 , vol. 22, # 2 p. 185 - 191
反应条件
1: 60.6 percent / POCl3 / 6 h / Heating
2: 18 percent / POCl3, diethylaniline / 40 h / Heating
3: 81.9 percent / potassium carbonate / aq. ethanol / 13 h / Heating
View Scheme
参考文献
Modnikova, G. A.; Titkova, R. M.; Glushkov, R. G.; Sokolova, A. S.; Silin, V. A.; Chernov, V. A.
Pharmaceutical Chemistry Journal, 1988 , vol. 22, # 2 p. 135 - 141
Khimiko-Farmatsevticheskii Zhurnal, 1988 , vol. 22, # 2 p. 185 - 191
