1: With methyl diphenyl silane; [Rh(Phebox-ph)] in toluene T=50°C; 1 h; Inert atmosphere; 2: With hydrogenchloride; water in toluene T=0 - 20°C; optical yield given as percent eeenantioselective reaction;
(S)-12-(hydroxymethyl)-14-methyl-1(5,8)-quinolina-4(1,4)-benzenacyclohexaphane in toluene T=20°C; 14 h; Product distribution; Further Variations:ReagentsTemperaturestime;