2,6-二溴-3-羟基吡啶合成路线 （共 17 条）
反应条件
sodium hydroxide; bromine 1.) 0 deg C, 0.5 h, 2.) RT, 2 h;
参考文献
Clark, Gary J.; Deady, Leslie W.
Australian Journal of Chemistry, 1981 , vol. 34, # 4 p. 927 - 932
反应条件
bromine in sodium hydroxide; water; ethyl acetate
参考文献
Wishka, Donn G.; Reitz, Steven Charles; Piotrowski, David W.; Groppi JR., Vincent E.
Patent: US2003/45540 A1, 2003 ;
反应条件
sodium hydroxide; bromine in water 0.5 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Synthesis, , # 6 p. 497 - 498
反应条件
N-bromosuccinmide in tetrachloromethane T=20°C; 24 h;
参考文献
Synthesis, , # 14 p. 2175 - 2179
反应条件
N-bromosuccinmide in tetrachloromethane T=20°C; 48 h;
参考文献
Synthesis, , # 14 p. 2175 - 2179
反应条件
sodium hydroxide; bromine in water 3 h;
参考文献
Koch; Schnatterer
Synthesis, 1990 , # 6 p. 497 - 498
反应条件
water; hydrogen bromide T=130°C; unter Druck;
参考文献
Recueil des Travaux Chimiques des Pays-Bas, , vol. 69, p. 1281,1286
参考文献
Recueil des Travaux Chimiques des Pays-Bas, , vol. 69, p. 1281,1286
反应条件
1: 92 percent / K2CO3 / acetone / 1.5 h / Heating 2: Bu3SnH, AIBN / toluene / 20 h / 95 °C View Scheme
参考文献
Bolm, Carsten; Ewald, Martina; Zehnder, Margareta; Neuburger, Markus A.
Chemische Berichte, 1992 , vol. 125, # 2 p. 453 - 458
反应条件
1: 79 percent / potassium carbonate / dimethylsulfoxide / 1 h / Heating 2: 45 percent / nitric acid, conc. sulfuric acid / 2 h / 60 - 65 °C 3: 63 percent / hydrazine hydrate / Pd/C / ethanol / 0.5 h / Heating View Scheme
参考文献
Clark, Gary J.; Deady, Leslie W.
Australian Journal of Chemistry, 1981 , vol. 34, # 4 p. 927 - 932
