1: 99 percent / triethylamine / CH2Cl2 / 1 h / -10 - -5 °C 2: 90 percent / NaI / acetonitrile / 1 h / Heating 3: 95 percent / NaH / dimethylformamide / 1 h / 0 deg C -> r.t. 4: 89 percent / 85percent KOH / methanol; H2O / 3 h / Heating View Scheme

1: 99 percent / triethylamine / CH2Cl2 / 1 h / -10 - -5 °C 2: 90 percent / NaI / acetonitrile / 1 h / Heating 3: 95 percent / NaH / dimethylformamide / 1 h / 0 deg C -> r.t. 4: 89 percent / 85percent KOH / methanol; H2O / 3 h / Heating 5: 91 percent / HCl / 1.5 h / 0 -> 25 deg C 6: 68 percent / 1 h / 270 °C View Scheme