5-氯-3-(二氟甲基)-1-甲基-1H-吡唑-4-甲醛合成路线 （共 4 条）
反应条件
trichlorophosphate in DMF (N,N-dimethyl-formamide) T=0 - 20°C; 4 h;
参考文献
Takahashi, Satoru; Ueno, Ryohei; Yamaji, Yoshihiro; Fujinami, Makoto
Patent: US2005/256004 A1, 2005 ;
Location in patent: Page/Page column 33 ;
反应条件
trichlorophosphate T=120°C; 0.666667 h; Cooling with ice;
参考文献
EISAI RandD MANAGEMENT CO., LTD.; SPYVEE, Mark; SATOH, Takashi; CARLSON, Jonathan Eric
Patent: WO2012/39972 A1, 2012 ;
Location in patent: Page/Page column 22 ;
WO 2012/039972 A1
反应条件
1: With trichlorophosphate in toluene 3 h; CoolingReflux; 2: With sodium hydrogencarbonate in water; ethyl acetate
参考文献
Bayer CropScience AG
Patent: US2011/207940 A1, 2011 ;
Location in patent: Page/Page column 5 ;
反应条件
1: With dihydrogen peroxide; sodium hydroxide in water; toluene T=37 - 50°C; 7 h; 2: With hydrogenchloride in water pH=2;
参考文献
BAYER CROPSCIENCE AG; BENTING, Juergen; COQUERON, Pierre-Yves; CRISTAU, Pierre; DAHMEN, Peter; DESBORDES, Philippe; GARY, Stephanie; GREUL, Joerg; HADANO, Hiroyuki; MEISSNER, Ruth; WACHENDORFF-NEUMANN, Ulrike
Patent: WO2011/151370 A1, 2011 ;
Location in patent: Page/Page column 90 ;
