2-甲基吡啶-4-硼酸频哪酯合成路线 （共 5 条）
反应条件
potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in DMF (N,N-dimethyl-formamide) T=80°C; 12 h;
参考文献
WO2004/14913 A2, ;
Page 82 ;
WO 2004/014913 A2
反应条件
potassium acetate; bis(dibenzylideneacetone)-palladium(0); tri-cyclo-hexyl-phosphine in 1,4-dioxane T=90°C; Inert atmosphere;
参考文献
WO2009/137404 A1, ;
Page/Page column 33 ;
WO 2009/137404 A1
反应条件
(iPrPNP)CoCH2SiMe3 in tetrahydrofuran T=80°C; 24 h; Inert atmosphereGlovebox; Overall yield = 92 percent; Overall yield = 0.111 g;
参考文献
Journal of the American Chemical Society, , vol. 136, # 11 p. 4133 - 4136
反应条件
sodium periodate; ammonium acetate in water; acetone T=20°C; 12 h;
参考文献
MEMORY PHARMACEUTICALS CORPORATION
Patent: WO2004/14913 A2, 2004 ;
Location in patent: Page 82-83 ;
WO 2004/014913 A2
反应条件
caesium carbonate; tetrakis(triphenylphosphine) palladium(0) in ethylene glycol dimethyl ether; water
16 h; Reflux;
参考文献
Van Brandt, Sven Franciscus Anna; De Cleyn, Michel Anna Jozef; Gijsen, Henricus Jacobus Maria; Berthelot, Didier Jean-Claude; Surkyn, Michel
Patent: US2012/295891 A1, 2012 ;
Location in patent: Page/Page column 31 ;
