反应条件
1: 75 percent / NaH / petroleum ether / Heating
2: 85 percent / H+
3: 42 percent / 5N NaOH / tetrahydrofuran / 20 h / Heating
4: 72 percent / diethyl ether / 1.) 0 deg C, 1 h, 2.) RT, overnight
5: 1.) n-BuLi / 1.) THF, ether, 2a.) 0 deg C, 2 h, 2b.) RT, 2 h
6: 76 percent / 5N HCl / pentane / 2 h
View Scheme
参考文献
Manfredi, Kirk; Gingerich, S. B.; Jennings, P. W.
Journal of Organic Chemistry, 1985 , vol. 50, # 4 p. 535 - 537
