反应条件
1: LiClO4*3H2O, tributylphosphine oxide / toluene / Heating
2: 30 percent H2O2, KOH / methanol / Ambient temperature
3: 1.) t-BuOK / 1.) THF, r.t., 2.) r.t.
4: 94 percent / lithium diisopropylamide / tetrahydrofuran / 1.) -60 deg C, 2.) 0 deg C
5: 1.) oxalyl dichloride, DMSO, 2.) Et3N / 1.) CH2Cl2, -60 deg C, 2.) -60 deg C
6: 62 percent / p-TsOH*H2O / dimethylsulfoxide / 3 h / 100 °C
View Scheme
参考文献
Satoh, Tsuyoshi; Kawase, Yasushi; Yamakawa, Koji
Bulletin of the Chemical Society of Japan, 1991 , vol. 64, # 4 p. 1129 - 1135
