4-甲氧基三氟甲烷磺酸苯酯合成路线 （共 120 条）
反应条件
tetrabutyl ammonium fluoride; bis(dibenzylideneacetone)-palladium(0); 2-dicyclohexylphosphino-1,1'-biphenyl in 1,4-dioxane
6 h; Heating;
参考文献
Seganish, W. Michael; DeShong, Philip
Journal of Organic Chemistry, 2004 , vol. 69, # 4 p. 1137 - 1143
反应条件
potassium phosphate; tris(dibenzylideneacetone)dipalladium (0); N-[2'-(dicyclohexylphosphino)-1,1'-biphenyl-2-yl]-N,N-dimethylamine in toluene
T=100°C; Arylation;
参考文献
Old, David W.; Harris, Michele C.; Buchwald, Stephen L.
Organic Letters, 2000 , vol. 2, # 10 p. 1403 - 1406
反应条件
caesium carbonate; tri-cyclo-hexyl-phosphine; palladium diacetate in tetrahydrofuran
Suzuki-Miyaura reaction; 40 h; Heating;
参考文献
Molander, Gary A.; Petrillo, Daniel E.; Landzberg, Nicole R.; Rohanna, John C.; Biolatto, Betina
Synlett, 2005 , # 11 art. no. Y00205ST, p. 1763 - 1766
反应条件
1: Pd(PPh3)4; Et3N / dimethylformamide / 6 h / 60 °C
2: 74 percent Chromat. / CuCl / dimethylformamide / 12 h / 60 °C
View Scheme
参考文献
Nishihara, Yasushi; Ikegashira, Kazutaka; Hirabayashi, Kazunori; Ando, Jun-Ichi; Mori, Atsunori; Hiyama, Tamejiro
Journal of Organic Chemistry, 2000 , vol. 65, # 6 p. 1780 - 1787
反应条件
1,3,5,7-tetra-azatricyclo[5.1.1.13,5]decane; dnpf; bis(dibenzylideneacetone)-palladium(0) in tetrahydrofuran
T=80°C; Heck Reaction; 20 h; Inert atmosphere;
参考文献
Zou, Yinjun; Qin, Liena; Ren, Xinfeng; Lu, Yunpeng; Li, Yongxin; Zhou, Jianrong
Chemistry - A European Journal, 2013 , vol. 19, # 10 p. 3504 - 3511
反应条件
palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl; sodium t-butanolate in toluene
T=80°C;
参考文献
Wolfe, John P.; Buchwald, Stephen L.
Journal of Organic Chemistry, 1997 , vol. 62, # 5 p. 1264 - 1267
反应条件
palladium diacetate; caesium carbonate; 2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl in toluene
T=80°C; 16 h;
参考文献
Navarro, Oscar; Kaur, Harneet; Mahjoor, Parisa; Nolan, Steven P.
Journal of Organic Chemistry, 2004 , vol. 69, # 9 p. 3173 - 3180
反应条件
caesium carbonate; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene; tris(dibenzylideneacetone)dipalladium (0) in 1,4-dioxane
15 h; Heating;
参考文献
Itoh, Takahiro; Mase, Toshiaki
Organic Letters, 2004 , vol. 6, # 24 p. 4587 - 4590
反应条件
tetrakis(triphenylphosphine) palladium(0); copper(l) chloride in N,N-dimethyl-formamide
T=80°C; 12 h;
参考文献
Nishihara, Yasushi; Ikegashira, Kazutaka; Mori, Atsunori; Hiyama, Tamejiro
Chemistry Letters, 1997 , # 12 p. 1233 - 1234
反应条件
1: Pd(PPh3)4; Et3N / dimethylformamide / 6 h / 60 °C
2: 51 percent / CuCl; Pd(PPh3)4 / dimethylformamide / 12 h / 80 °C
View Scheme
参考文献
Nishihara, Yasushi; Ikegashira, Kazutaka; Hirabayashi, Kazunori; Ando, Jun-Ichi; Mori, Atsunori; Hiyama, Tamejiro
Journal of Organic Chemistry, 2000 , vol. 65, # 6 p. 1780 - 1787
