4-甲氧基三氟甲烷磺酸苯酯合成路线 （共 120 条）
反应条件
1,3-bis-(diphenylphosphino)propane; triethylamine; bis-triphenylphosphine-palladium(II) chloride in N,N-dimethyl-formamide T=150°C; 6 h; sealed tube;
参考文献
Hagiwara, Hisahiro; Eda, Yasushi; Morohashi, Kimie; Suzuki, Toshio; Ando, Masayoshi; Ito, Nobuhiko
Tetrahedron Letters, 1998 , vol. 39, # 23 p. 4055 - 4058
反应条件
pyridine; 2,6-di-tert-butyl-4-methyl-phenol; pyridine hydrogenfluoride; lithium chloride; tetrakis(triphenylphosphine) palladium(0) 1.) 1,4-dioxane, reflux, 6.5 h, 2.) THF, 23 deg C, 16 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Echavarren,A.M.; Stille,J.K.
Journal of the American Chemical Society, 1987 , vol. 109, p. 5478
反应条件
ammonium hydroxide; 2,6-di-tert-butyl-4-methyl-phenol; lithium chloride; tetrakis(triphenylphosphine) palladium(0) 1.) 1,4-dioxane, reflux, 85 deg C, 13 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Echavarren,A.M.; Stille,J.K.
Journal of the American Chemical Society, 1987 , vol. 109, p. 5478
反应条件
potassium fluoride; palladium diacetate in toluene T=80°C; Suzuki-Miyaura coupling; 3 h;
参考文献
TAKASAGO INTERNATIONAL CORPORATION
Patent: WO2004/72088 A2, 2004 ;
Location in patent: Page/Page column 49 ;
反应条件
copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); cesium fluoride in N,N-dimethyl-formamide T=45°C; Stille reaction; 2 h;
参考文献
Mee, Simon P. H.; Lee, Victor; Baldwin, Jack E.
Angewandte Chemie - International Edition, 2004 , vol. 43, # 9 p. 1132 - 1136
反应条件
sodium carbonate; palladium on activated charcoal in ethanol; water T=20°C; Suzuki-Miyaura cross-coupling; 48 h;
参考文献
Kitamura, Yoshiaki; Sakurai, Ai; Udzu, Takahiro; Maegawa, Tomohiro; Monguchi, Yasunari; Sajiki, Hironao
Tetrahedron, 2007 , vol. 63, # 43 p. 10596 - 10602
反应条件
tetrabutyl ammonium fluoride; 2-dicyclohexylphosphino-1,1'-biphenyl; bis(dibenzylideneacetone)-palladium(0) in tetrahydrofuran 24 h; Heating;
参考文献
Riggleman, Shaundra; DeShong, Philip
Journal of Organic Chemistry, 2003 , vol. 68, # 21 p. 8106 - 8109
反应条件
tetrabutyl ammonium fluoride; 2-dicyclohexylphosphino-1,1'-biphenyl; bis(dibenzylideneacetone)-palladium(0) in tetrahydrofuran 12 h; Heating;
参考文献
Riggleman, Shaundra; DeShong, Philip
Journal of Organic Chemistry, 2003 , vol. 68, # 21 p. 8106 - 8109
反应条件
caesium carbonate; tri-cyclo-hexyl-phosphine; palladium diacetate in tetrahydrofuran Suzuki-Miyaura reaction; 20 h; Heating;
参考文献
Molander, Gary A.; Petrillo, Daniel E.; Landzberg, Nicole R.; Rohanna, John C.; Biolatto, Betina
Synlett, 2005 , # 11 art. no. Y00205ST, p. 1763 - 1766
反应条件
potassium phosphate; triphenylphosphine; palladium diacetate in N,N-dimethyl-formamide T=90°C; 1 h;
参考文献
Rao, Maddali L.N.; Banerjee, Debasis; Jadhav, Deepak N.
Tetrahedron Letters, 2007 , vol. 48, # 38 p. 6644 - 6647
