4-甲氧基三氟甲烷磺酸苯酯合成路线 （共 120 条）
反应条件
palladium diacetate; 1,3-bis-(diphenylphosphino)propane; triethylamine in N,N-dimethyl-formamide
T=80°C; 16 h;
参考文献
Larhed, Mats; Hallberg, Anders
Journal of Organic Chemistry, 1997 , vol. 62, # 22 p. 7858 - 7862
反应条件
tetrabutyl ammonium fluoride; bis(dibenzylideneacetone)-palladium(0); 2-dicyclohexylphosphino-1,1'-biphenyl in tetrahydrofuran
6 h; Heating;
参考文献
Seganish, W. Michael; DeShong, Philip
Journal of Organic Chemistry, 2004 , vol. 69, # 4 p. 1137 - 1143
反应条件
potassium carbonate; silver(l) oxide; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in tetrahydrofuran
T=80°C; Suzuki-Miyaura coupling;
参考文献
Zou, Gang; Reddy, Y. Krishna; Falck
Tetrahedron Letters, 2001 , vol. 42, # 41 p. 7213 - 7215
反应条件
triethylamine; acetone in 2,2,2-trifluoroethanol
60 h; Irradiation;
参考文献
Protti, Stefano; Fagnoni, Maurizio; Albini, Angelo
Angewandte Chemie - International Edition, 2005 , vol. 44, # 35 p. 5675 - 5678
反应条件
potassium carbonate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct in tetrahydrofuran; water
Suzuki coupling reaction; 18 h; Heating;
参考文献
Molander, Gary A.; Yun, Chang-Soo
Tetrahedron, 2002 , vol. 58, # 8 p. 1465 - 1470
反应条件
dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct; water; caesium carbonate in tetrahydrofuran
Suzuki-Miyaura cross-coupling reaction; 72 h; Heating;
参考文献
Molander, Gary A.; Yun, Chang-Soo; Ribagorda, Maria; Biolatto, Betina
Journal of Organic Chemistry, 2003 , vol. 68, # 14 p. 5534 - 5539
反应条件
palladium diacetate; caesium carbonate; tris(4-methylphenyl)-phosphine in toluene
8 h; Heating;
参考文献
Hayashi, Sayuri; Hirano, Koji; Yorimitsu, Hideki; Oshima, Koichiro
Journal of the American Chemical Society, 2006 , vol. 128, # 7 p. 2210 - 2211
反应条件
potassium phosphate; 2nd generation X-Phos precatalyst in tetrahydrofuran; water
T=20°C; Suzuki-Miyaura cross-coupling; 0.5 h; Inert atmosphere;
参考文献
Kinzel, Tom; Zhang, Yong; Buchwald, Stephen L.
Journal of the American Chemical Society, 2010 , vol. 132, # 40 p. 14073 - 14075
反应条件
potassium phosphate; biphenyl-2-yl-di-tert-butyl-phosphane; tris(dibenzylideneacetone)dipalladium (0) in ethylene glycol dimethyl ether
T=80°C; Arylation; 16 h;
参考文献
Wolfe, John P.; Tomori, Hiroshi; Sadighi, Joseph P.; Yin, Jingjun; Buchwald, Stephen L.
Journal of Organic Chemistry, 2000 , vol. 65, # 4 p. 1158 - 1174
反应条件
1: Pd(PPh3)4; Et3N / dimethylformamide / 6 h / 60 °C
2: 64 percent Chromat. / CuCl; Pd(PPh3)4 / dimethylformamide / 80 °C
View Scheme
参考文献
Nishihara, Yasushi; Ikegashira, Kazutaka; Hirabayashi, Kazunori; Ando, Jun-Ichi; Mori, Atsunori; Hiyama, Tamejiro
Journal of Organic Chemistry, 2000 , vol. 65, # 6 p. 1780 - 1787
