1-甲基-1H-吡唑-5-甲腈合成路线 （共 9 条）
反应条件
in acetonitrile Irradiation;
参考文献
Barltrop, John A.; Day, A. Colin; Mack, Arthur G.; Shahrisa, Aziz; Wakamatsu, Shigeru
Journal of the Chemical Society, Chemical Communications, 1981 , # 12 p. 604 - 606
反应条件
magnesium 1) ether, 2) ether, 30 min, reflux; Yield given. Multistep reaction;
参考文献
Manaev, Yu. A.; Khrapov, A. V.; Perevalov, V. P.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1991 , vol. 27, # 6 p. 656 - 658
Khimiya Geterotsiklicheskikh Soedinenii, 1991 , vol. 27, # 6 p. 833 - 835
反应条件
pyridine; trichlorophosphate
T=20°C; 3 h;
参考文献
PFIZER INC.
Patent: WO2006/43145 A1, 2006 ;
Location in patent: Page/Page column 120 ;
WO 2006/043145 A1
反应条件
in water
T=25°C; 1 h; Yield given;
参考文献
Bruix, Marta; Castellanos, M. Luisa; Martin, M. Rosario; Mendoza, Javier de
Tetrahedron Letters, 1985 , vol. 26, # 44 p. 5485 - 5488
反应条件
1: 80 percent / cc. aq. ammonium hydroxide / Ambient temperature
2: 82 percent / phosphoryl chloride / pyridine / 2 h / -5 °C
View Scheme
参考文献
Castellanos, Maria Luisa; Llinas, Montserrat; Bruix, Marta; Mendoza, Javier de; Martin, M. Rosario
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 1209 - 1216
反应条件
in methanol
30 h; electrooxidation;
参考文献
Yoshida, Kunihisa; Toyo-oka, Yoshimasa; Takeda, Kazusada
Journal of Heterocyclic Chemistry, 1995 , vol. 32, # 2 p. 701 - 702
反应条件
in chloroform; water
0.0166667 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Castellanos, Maria Luisa; Llinas, Montserrat; Bruix, Marta; Mendoza, Javier de; Martin, M. Rosario
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1985 , p. 1209 - 1216
反应条件
30 h; electrooxidation;
参考文献
Yoshida, Kunihisa; Toyo-oka, Yoshimasa; Takeda, Kazusada
Journal of Heterocyclic Chemistry, 1995 , vol. 32, # 2 p. 701 - 702
反应条件
in acetonitrile
Irradiation;
参考文献
Barltrop, John A.; Day, A. Colin; Mack, Arthur G.; Shahrisa, Aziz; Wakamatsu, Shigeru
Journal of the Chemical Society, Chemical Communications, 1981 , # 12 p. 604 - 606
