2,5-二氧代吡咯烷-1-基4-氟苯甲酸合成路线 （共 7 条）
反应条件
[bis(acetoxy)iodo]benzene in ethyl acetate
0.5 h; cooling;
参考文献
Wang, Naiwei; Liu, Renhua; Xu, Qing; Liang, Xinmiao
Chemistry Letters, 2006 , vol. 35, # 6 p. 566 - 567
反应条件
dicyclohexyl-carbodiimide in tetrahydrofuran
T=20°C; 12 h; Inert atmosphere;
参考文献
Dissoki, Samar; Hagooly, Aviv; Elmachily, Smadar; Mishani, Eyal
Journal of Labelled Compounds and Radiopharmaceuticals, 2011 , vol. 54, # 11 p. 693 - 701
反应条件
pyridine in acetonitrile
T=20°C; 1.5 h;
参考文献
Azarian, Vahe; Gangloff, Anne; Seimbille, Yann; Delaloye, Sibylle; Czernin, Johannes; Phelps, Michael E.; Silverman, Daniel H. S.
Journal of Labelled Compounds and Radiopharmaceuticals, 2006 , vol. 49, # 3 p. 269 - 283
反应条件
2,2,6,6-tetramethyl-1-piperidinyloxy, free radical; 1-trifluoromethyl-3-methoxybenzene; cesium fluoride in N,N-dimethyl-formamide
T=110°C; Inert atmosphere; Product distribution / selectivity;
参考文献
Carroll, Michael Andrew; Yan, Ran
Patent: US2009/286992 A1, 2009 ;
Location in patent: Page/Page column 7 ;
反应条件
in diethyl ether
T=20°C;
参考文献
Riss, Patrick J.; Lu, Shuiyu; Telu, Sanjay; Aigbirhio, Franklin I.; Pike, Victor W.
Angewandte Chemie - International Edition, 2012 , vol. 51, # 11 p. 2698 - 2702
参考文献
Al Jammaz; Al-Otaibi; Okarvi; Amartey
Journal of Labelled Compounds and Radiopharmaceuticals, 2006 , vol. 49, # 2 p. 125 - 137
反应条件
N-ethyl-N,N-diisopropylamine in N,N-dimethyl-formamide
T=20°C; 18 h;
参考文献
Pathuri, Gopal; Agashe, Hrushikesh B.; Awasthi, Vibhudutta; Gali, Hariprasad
Journal of Labelled Compounds and Radiopharmaceuticals, 2010 , vol. 53, # 4 p. 186 - 191
